Furosemide Injection USP – Potent Loop Diuretic for Rapid Edema Relief

• Customization: Available
• Application: Internal Medicine
• Usage Mode: for Injection
• Model NO.: SD-G-B-2031
• Suitable for: Elderly, Children, Adult
• State: Liquid
• Shape: Liquid
• Type: Inorganic Chemicals
• Pharmaceutical Technology: Chemical Synthesis
• Drug Reg./Approval No.: Z02
• Drug Ad Approval No.: Z02
• Transport Package: 10× 10 Tablets/Box
• Specification: 40mg
• Trademark: Sinopharmatech
• Origin: Shandong, China
• HS Code: 300490
• Production Capacity: 5000000 Pieces/Month

Product Description

PRODUCT NAME:	Furosemide Tablets
STRENGTH:	20mg/2ml
PACKING DETAILS:	10 vials/box
STORAGE:	Store in a cool and dry place below 25ºC, protected from light.
SHELF LIFE:	36 months
REGISTRATION DOSSIERS ARE AVAILABLE.
CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE.

Furosemide - Indications, Dosage & Administration, and Storage

1. Pharmacological Action

• Mechanism:
  Potent loop diuretic that inhibits the Na/K/2Cl cotransporter in the ascending limb of the loop of Henle, resulting in profound diuresis.

• Therapeutic Effects:

  • Rapid reduction of fluid overload

  • Decreased systemic/pulmonary congestion

  • Blood pressure control

2. Indications

• Edema (cardiac, hepatic, or renal origin)

• Hypertension (adjunctive therapy)

• Acute pulmonary edema (IV form)

• Hypercalcemia (adjunct treatment)

3. Dosage & Administration

Adults:

• Oral (tablets):

  • Initial: 20-80 mg as single morning dose

  • Maintenance: 20-120 mg/day (max 600 mg/day in divided doses)

• IV/IM:

  • Acute edema: 20-40 mg slow IV push (may repeat in 2 hrs)

  • Continuous infusion: 10-40 mg/hr (for refractory cases)

Pediatrics:

• Oral: 1-2 mg/kg/dose (max 6 mg/kg/day)

• IV: 0.5-1 mg/kg/dose (max 6 mg/kg/day)

Special Populations:

• Renal impairment: Reduce frequency (not dose)

• Elderly: Start with lower doses

4. Storage Requirements

• Tablets:

  • Store below 25°C (77°F)

  • Protect from light and moisture

  • Keep container tightly closed

• Injection:

  • Unopened vials: Room temperature (15-30°C) or refrigerated (2-8°C)

  • Do not freeze

  • Use immediately after opening
     

5. Important Safety Information

• Contraindications:

  • Anuria

  • Hepatic coma

  • Severe electrolyte depletion

  • Hypersensitivity to sulfonamides

• Monitoring Parameters:

  • Serum electrolytes (K,Na, Mg)

  • Renal function

  • Blood pressure

  • Hearing (with high doses)

• Drug Interactions:

  • Aminoglycosides (↑ ototoxicity risk)

  • Digoxin (↑ toxicity with hypokalemia)

  • NSAIDs (↓ diuretic effect)

  • Lithium (↑ lithium levels)

6. Adverse Effects

• Common: Dehydration, hypokalemia, hypotension

• Serious: Ototoxicity (with rapid IV), pancreatitis, Stevens-Johnson syndrome