Sermorelin Peptide Therapy - Anti-Aging Gro*Wth Hormone Releasing Factor for Vitality & Wellness

• Customization: Available
• Application: Salon
• Disposable: Injection
• Model NO.: SD-G-B-20251
• Gender: Unisex
• Side Effect: Dry Mouth
• Usage: Injection
• Pharmaceutical Technology: Chemical Synthesis
• Efficacy: Metabolic Booster
• Health Food Approval No.: Z02
• Transport Package: Ampoule Vial
• Specification: 5mg/vial*10vials
• Origin: Shandong, China
• HS Code: 30049090
• Production Capacity: 5000000 Pieces/Month

Product Description

Product Name	Sermorelin
Active Ingredient	Sermorelin
Dosage Form	Injection
Strength	5 mg per vial
Manufacturer	Sinopharmatech Co., Ltd.

 

   

Mechanism of Action

Sermorelin is a synthetic 29-amino acid peptide analog of naturally occurring gro*wth hor*mo*ne-re*lea*sing hor*mone (G*H*R*H*). Its primary function is to stimulate the anterior pituitary gland to secrete endogenous growth hormone (GH) by binding to G*H*R*H* receptors. Unlike exogenous GH therapy, Sermorelin preserves the physiological feedback loop of the hypothalamic-pituitary-somatostatin axis, preventing supraphysiological GH levels and maintaining circadian rhythm. This mechanism ensures a more natural secretion pattern, reducing risks associated with hormone imbalance.
Key pathways include:

• GH Secretion: Sermorelin activates adenylate cyclase, increasing cyclic AMP (cAMP) levels, which triggers GH release.
• IGF-1 Regulation: Elevated GH stimulates insulin-like growth factor-1 (IGF-1) production in the liver, promoting anabolic effects such as mus*cle gro*wth, tissue repair, and bone density.
• Metabolic Impact: Enhances lipolysis, improves insulin sensitivity, and supports cognitive function via neuroprotective effects.

2. Therapeutic Applications and Future Prospects
Current Clinical Uses

1. Growth Hormone Deficiency (GHD):
   • Pediatric GHD: Sermorelin stimulates linear growth in children with idiopathic or congenital GHD.
   • Adult GHD: Addresses symptoms like fatigue, reduced muscle mass, and impaired metabolism by restoring GH pulsatility.
2. Anti-Aging and Wellness:
   • Mitigates age-related GH decline, improving skin elasticity, energy levels, and sleep quality.
   • May reduce visceral adiposity and enhance cognitive function in elderly populations.
3. Sports Medicine and Rehabilitation:
   • Accelerates muscle recovery post-injury and enhances athletic performance by promoting collagen synthesis and reducing inflammation.

Emerging Research Directions

• Cardiovascular Health: Preclinical studies suggest Sermorelin may improve endothelial function and reduce atherosclerosis risk.
• Neurodegenerative Diseases: Investigated for its potential to cross the blood-brain barrier and protect against Alzheimer's and Parkinson's via neurotrophic effects.
• Immunomodulation: Early trials explore its role in enhancing immune response in immunocompromised patients.

3. Dosage and Administration
Standard Protocols

• Route: Subcutaneous injection, typically administered nightly to align with natural GH secretion peaks.
• Initial Dose: 0.1-0.3 mg/day (100-300 mcg) for 1-2 weeks to assess tolerance.
• Maintenance Dose: 0.2-0.5 mg/day (200-500 mcg), 5-7 times weekly, with cycles lasting 3-6 months.
• Combination Therapy: Often paired with G*H*R*P*s (e.g., G*H*R*P*-2) to amplify GH release synergistically.

Individualization

• Age and Weight: Lower doses (e.g., 0.1 mg/day) for elderly or metabolically compromised patients.
• Monitoring: Serum IGF-1 levels and clinical response guide dose adjustments.

4. Storage and Stability

• Refrigeration: Store lyophilized powder at 2-8°C (36-46°F); reconstituted solutions remain stable for 14 days under refrigeration.
• Room Temperature: Up to 25°C (77°F) for ≤72 hours if refrigeration is unavailable.
• Avoid Freezing: Freezing denatures the peptide, rendering it ineffective.
• Light Protection: Keep in opaque containers to prevent photodegradation.

5. Safety and Considerations

• Side Effects: Mild injection-site reactions, headaches, or transient hyperglycemia.
• Contraindications: Active malignancy, untreated hypothyroidism, or hypersensitivity to Sermorelin.
• Long-Term Use: Requires periodic bone density and glucose tolerance assessments.

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Why Choose Us?
High Purity (≥98%)
Flexible Dosing Options
GMP-Certified Quality
Weekly Dosing for Convenience