| Customization: | Available |
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| Application: | Internal Medicine |
| Usage Mode: | Infusion |
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Metronidazole IV Infusion 500mg/100ml is a widely used antimicrobial medication designed to combat various bacterial and protozoal infections. It is particularly effective against anaerobic bacteria, which thrive in environments with little to no oxygen, and certain protozoa, making it a vital treatment option in clinical settings. This intravenous formulation ensures rapid absorption and effectiveness in treating serious infections that require immediate medical intervention.
Pharmacology and Mechanism of Action
Metronidazole belongs to the nitroimidazole class of antibiotics and works by interfering with the DNA synthesis of bacteria and protozoa. Once inside the microbial cell, metronidazole undergoes a reduction reaction, leading to the formation of reactive nitrogen species. These reactive compounds bind to microbial DNA, causing strand breakage, inhibition of nucleic acid synthesis, and ultimately, cell death. This selective toxicity allows metronidazole to be highly effective against anaerobic bacteria and certain protozoa while having minimal effects on human cells.
Therapeutic Indications
Metronidazole IV Infusion is commonly prescribed for the treatment of the following infections:
1. Anaerobic Bacterial Infections
• Bacterial septicemia
• Intra-abdominal infections (peritonitis, abscesses)
• Gynecological infections (endometritis, pelvic inflammatory disease)
• Respiratory tract infections (aspiration pneumonia, lung abscess)
• Skin and soft tissue infections
• Bone and joint infections (osteomyelitis)
• Central nervous system infections (brain abscess, meningitis)
2. Protozoal Infections
• Amoebiasis (caused by Entamoeba histolytica)
• Giardiasis (caused by Giardia lamblia)
• Trichomoniasis (caused by Trichomonas vaginalis)
3. Surgical Prophylaxis
• Used to prevent postoperative infections, especially in colorectal surgery, gynecological procedures, and dental surgery.
| Active Ingredient | Metronidazole |
| Dosage Form | IV |
| Strength | 500mg/100 ml |
| Manufacturer | Sinopharmatech Co., Ltd. |
Available in various packaging options, customisable based on market requirements.
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