Customization: | Available |
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Application: | Internal Medicine |
Usage Mode: | For oral administration |
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PRODUCT NAME: | Co-trimoxazole 480 |
STRENGTH: | Sulfamethoxazole and Trimethoprim Tablets BP 400mg/80mg per tablet |
PACKING DETAILS: | 20 Tablets/Blister × 1 0Blister/Box |
STORAGE: | Store in a cool and dry place below 25ºC, protected from light. |
SHELF LIFE: | 36 months |
REGISTRATION DOSSIERS ARE AVAILABLE. | |
CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE. |
Sulfamethoxazole (SMZ) and Trimethoprim (TMP) work synergistically as a combined antibiotic by blocking two consecutive steps in bacterial folate synthesis:
Sulfamethoxazole inhibits dihydropteroate synthase, preventing folic acid formation.
Trimethoprim inhibits dihydrofolate reductase, blocking folate utilization.
This dual action provides bactericidal effects against a broad spectrum of Gram-positive and Gram-negative bacteria.
Urinary tract infections (UTIs)
Acute bronchitis exacerbations
Traveler's diarrhea
MRSA skin infections
Standard Adult Dose (UTI/Bronchitis):
1 tablet (400mg SMZ/80mg TMP) every 12 hours for 5-14 days.
Pediatric Dose:
Based on weight (6-12 mg TMP/kg/day) - use pediatric suspension if available.
Note: Take with a full glass of water; avoid sunlight (photosensitivity risk).
Store below 30°C in original packaging.
Protect from moisture and light.
Keep out of reach of children.