High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g

Product Details
Customization: Available
Type: Beauty Salon
Function: Moisturizer, Anti-Aging, Whitening/Lightening, Acne Treatment, Firming, Nourishing, Anti-Wrinkle
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Management System Certification
ISO 9001, ISO 9000, GMP, HACCP, BREEAM
Export Year
2016-07-01
  • High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g
  • High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g
  • High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g
  • High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g
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Basic Info.

Model NO.
SINOHM02158
Main Ingredient
Glutathione
Group
Middle-aged and Old
Certification
CE, FDA, GMP
Quality Guarantee Period
Three Years
Store Method
Normal Temperature
Formula
Ultra Strength
Quality Control
European or Us-FDA Standard
Usage
Moisturizer, Anti-Aging, Whitening/Lightening
MOQ
5000 Boxes
OEM Service
Available
Registration Dossiers
Available
Factory Inspection
Available
Sample
Available
Route
Injection
Medical Device Regulatory Type
Type 3
Transport Package
10 Vials+10 AMPS/Box
Specification
500mg, 1000mg
Trademark
SUPER GLUTA
Origin
France
HS Code
3004909099
Production Capacity
1, 000, 000 Vials

Product Description

PRODUCT NAME: (New) SUPER GLUTA® (Glutathione for Injection)
STRENGTH: 300 / 600 / 900 / 1200 / 1500 / 1800 / 2400 / 3000mg/5000 mg
PACKING DETAILS: 10 Vials(Glutathione)+10 Ampoules(Vitamin C or Water for Injection) /box
STORAGE: Store in a cool and dry place below 25ºC, protected from light.
SHELF LIFE: 36 months
REGISTRATION DOSSIERS ARE AVAILABLE.
CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE.
 
1. Name of the medicinal product
Lyophilized Ascorbic Acid injection 500mg/5ml,500mg/7ml,  1000mg/10ml.

2. Qualitative and quantitative composition
Ascorbic Acid 10.0% w/v
For excipients, see 6.1

3. Pharmaceutical form
Solution for Injection


High Strength Anti-Aging Vitamin C Lyophilized Powder for Injection 1.0g




4. Clinical particulars
4.1 Therapeutic indications
The prevention and treatment of scurvy, or other conditions requiring vitamin C supplementation, where the deficiency is acute or oral administration is difficult.
4.2 Posology and method of administration
Route of Administration: Parenteral Adults
0.5 to 1g daily for scurvy, 200 to 500mg daily for preventative therapy.
Children
100 to 300mg daily for curative purposes, or 30mg daily for protective treatment.
Elderly
No special dosage requirements have been suggested.
4.3 Contraindications
Hyperoxaluria
4.4 Special warnings and precautions for use
Ascorbic acid should be given with care to patients with underlying renal failure due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.
Large doses of Ascorbic Acid have resulted in haemolysis in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
4.5 Interaction with other medicinal products and other forms of interaction
Drugs which induce tissue desaturation of ascorbic acid include aspirin, nicotine from cigarettes, alcohol, several appetite suppressants, iron, phenytoin, some anti-convulsant drugs, the oestrogen component of oral contraceptives and tetracycline. Large doses of ascorbic acid may cause the urine to become acidic causing unexpected renal tubular reabsorption of acidic drugs, thus producing an exaggerated response. Conversely basic drugs may exhibit decreased reabsorption resulting in a decreased therapeutic effect. Large doses may reduce the response to oral anticoagulants.
It has been reported that concurrent administration of ascorbic acid and fluphenazine has resulted in decreased fluphenazine plasma concentrations.
Ascorbic acid is a strong reducing agent and interferes with numerous laboratory tests based on oxidation - reduction reactions. Specialised references should be consulted for specific information on laboratory test interferences caused by ascorbic acid.
Ascorbic acid given in addition to desferrioxamine in patients with iron overload to achieve better iron excretion may worsen iron toxicity, particularly to the heart, early on in the treatment when there is excessive tissue iron. Therefore it is recommended that in patients with normal cardiac function ascorbic acid should not be given for the first month after starting desferrioxamine. Ascorbic acid should not be given in conjunction with desferrioxamine in patients with cardiac dysfunction.
Aspirin can reduce the absorption of ascorbic acid by approximately a third and decreases urinary excretion by about half. The clinical importance of this is uncertain.
Patients with kidney failure given aluminium antacids and oral citrate can develop a potentially fatal encephalopathy due to marked rise in blood aluminium levels. There is evidence that vitamin C may interact similarly.
Oral contraceptives lower serum levels of ascorbic acid.
4.6 Fertility, pregnancy and lactation
Ascorbic acid in doses greater than 1g daily should not be taken during pregnancy since the effect of large doses on the foetus is unknown. Ascorbic acid is excreted in breast milk, but there is no evidence of any hazard.
4.7 Effects on ability to drive and use machines
Ascorbic acid injection is unlikely to affect the patient's ability to drive or use machinery.
4.8 Undesirable effects
Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if the urine becomes acidic. Doses of 600mg or more daily have a diuretic action. Induced tolerance with prolonged use of large doses can result in symptoms of deficiency when intake is reduced to normal.
4.9 Overdose
Large doses may cause gastrointestinal disorders including diarrhoea. Large doses may also result in hyperoxaluria and renal oxalate calculi may form if urine is acidic. Doses of 600mg or more daily have a diuretic action. Stop treatment and treat symptomatically.

5. Pharmacological properties
5.1 Pharmacodynamic properties
ATC Code: A11G A01
Ascorbic acid, a water-soluble vitamin, is essential for formation of collagen and intercellular material, and therefore necessary for the development of cartilage, bone, teeth and for the healing of wounds. It is also essential for the conversion from folic acid to folinic acid, facilitates iron absorption from the gastro-intestinal tract and influences haemoglobin formation and erythrocyte maturation.
5.2 Pharmacokinetic properties
Distribution - widely distributed in body tissues with about 25% bound to plasma proteins. Large amounts are present in leucocytes and platelets. Ascorbic acid crosses the placenta.
Metabolism - readily oxidised to dehydroascorbic acid where some is metabolised to oxalic acid and the inactive ascorbate - 2 - sulphate. Metabolic turnover appears to be greater in females than males.
Excretion - large doses are rapidly excreted in the urine when in excess of the requirements of the body and after an intravenous dose, about 40% is excreted in 8 hours, which is increased to about 70% after tissue saturation. The amount of unchanged drug is dose dependent; in women the excretion of ascorbic acid appears to vary with the stage of the menstrual cycle and it is decreased when taking oral contraceptives.
Ascorbic acid is excreted in breast milk.
Oxalic acid and ascorbate - 2 - sulphate are excreted in the urine.
5.3 Preclinical safety data
None stated

6. Pharmaceutical particulars
6.1 List of excipients
Sodium Bicarbonate
Sodium Metabisulphite
Hydrochloric acid
Water for injections
6.2 Incompatibilities
Incompatible with ferric salts, oxidising agents, and salts of heavy metals, particularly copper.
Injections of ascorbic acid have been reported to be incompatible with aminophylline, bleomycin sulphate, erythromycin lactobionate, nafcillin sodium, nitrofurantoin sodium, conjugated oestrogens, sodium bicarbonate and sulphafurazole diethanolamine. Occasional incompatibility, depending on pH or concentration, has occurred with chloramphenicol sodium succinate.
6.3 Shelf life
12 months
6.4 Special precautions for storage
Do not store above 25°C
6.5 Nature and contents of container
5ml neutral glass (Type 1) ampoules. Pack size - 10.
6.6 Special precautions for disposal and other handling
None stated

Marketing Authorisation Holder:
Laboratories Viroche S.A. 

All Designed and formulated from France

Global Supplier and Exporter:
Shandong Sino Pharmaceutical Technology Co.,Ltd.

North of National Road 327, Liuhang Town, High-tech Zone, Jining, China.

Payment:  T/T or west union
Delivery time: within 2 working days for ready stocks, 45 working days for batch order.
Shipment: HKEMS,DHL,FEDEX,door to door service for some countries.

We are looking for the SUPER GLUTA® agents all around the world.
Welcome to join us!


Moreover, kindly note that we are always providing our customers with Consignment Manufacturing Serivce, OEM/ODM.

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